DAXXIFY™

Get ready for a newer innovative way to appear smoother without fine lines. Introducing DAXXIFY™ – the only long-lasting, peptide-powered frown line treatment and the first innovation of its kind in over 20 years.

Discover DAXXIFY™ & How It Is Different

At its core, DAXXIFY™ is an injectable, anti-wrinkle treatment system that helps target dynamic wrinkles on a patient’s face.
Nearly 90% of patients say they wish results lasted longer. With DAXXIFY™, you can keep your frown lines smoother for a full year with as few as 2 treatments.*Current on-the-market injectables last 3 – 4 months and require up to 4 treatments a year to maintain results.
The active ingredient in many of these products is botulinum toxin A. This ingredient smooths out moderate to severe frown lines on a patient’s face. But, botulinum must also be stabilized via either HSA or other alternative proteins. DAXXIFY™ became notable immediately for being the first product of its kind to use a novel peptide as a stabilizer, meaning that it doesn’t contain byproducts from either humans or animals of any kind.
DAXXIFY™ is FDA approved to help smooth moderate to severe lines between the brows. It is the only long-lasting frown line treatment powered by a peptide with results that last on average 6 months and up to 9 months for some.*
DAXXIFY™, The Long Lasting Cosmetic
Dermatology Frown Line Treatment
Get ready for a newer innovative way to appear smoother without fine lines. Introducing DAXXIFY™ – the only long-lasting, peptide-powered frown line treatment and the first innovation of its kind in over 20 years.

Discover DAXXIFY™ & How It Is Different

At its core, DAXXIFY™ is an injectable, anti-wrinkle treatment system that helps target dynamic wrinkles on a patient’s face.
Nearly 90% of patients say they wish results lasted longer. With DAXXIFY™, you can keep your frown lines smoother for a full year with as few as 2 treatments.*Current on-the-market injectables last 3 – 4 months and require up to 4 treatments a year to maintain results.
The active ingredient in many of these products is botulinum toxin A. This ingredient smooths out moderate to severe frown lines on a patient’s face. But, botulinum must also be stabilized via either HSA or other alternative proteins. DAXXIFY™ became notable immediately for being the first product of its kind to use a novel peptide as a stabilizer, meaning that it doesn’t contain byproducts from either humans or animals of any kind.
DAXXIFY™ is FDA approved to help smooth moderate to severe lines between the brows. It is the only long-lasting frown line treatment powered by a peptide with results that last on average 6 months and up to 9 months for some.*
AREAS OF TREATMENT: DAXXIFY™ is a prescription medicine that is injected into muscles and used in adults to temporarily improve the look of moderate to severe frown lines between the eyebrows.
AREAS OF TREATMENT: DAXXIFY™ is a prescription medicine that is injected into muscles and used in adults to temporarily improve the look of moderate to severe frown lines between the eyebrows.

DAXXIFY™

The long lasting cosmetic dermatology frown line treatment. DAXXIFY™ extends your treatment cycle. Get more than 6 months of smoother facial lines. At its core, DAXXIFY™ is an injectable, anti-wrinkle treatment system that helps target dynamic wrinkles on a patient’s face.

DAXXIFY™

The long lasting cosmetic dermatology frown line treatment. DAXXIFY™ extends your treatment cycle. Get more than 6 months of smoother facial lines. At its core, DAXXIFY™ is an injectable, anti-wrinkle treatment system that helps target dynamic wrinkles on a patient’s face.

Frequently Asked Questions

Q: What is DAXXIFY™ and how is it different?

A: DAXXIFY™ is FDA-approved to help smooth moderate to severe lines between the brows. It is the only long-lasting frown line treatment powered by a peptide with results that last on average 6 months and up to 9 months for some. Produced by Revance Therapeutics, Daxxify is a revolutionary new product.

Q: How is DAXXIFY™ different from Other frown line treatments?

A: DAXXIFY™ is the only long-lasting frown line treatment powered by a peptide. Results last on average 6 months and up to 9 months for some. † • All frown line treatments require a special ingredient to stabilize botulinum toxin A, the protein responsible for helping smooth moderate to severe frown lines. For instance, BOTOX® Cosmetic uses human serum albumin (HSA), a blood product, as its stabilizer. Dysport®, another frown line treatment, uses HSA as a stabilizer and cow’s milk protein as a protectant. • DAXXIFY™ is unique because it is the only formulation that uses a novel peptide as a stabilizer and does not contain human or animal byproducts. • †At least 50% of patients in clinical studies had no or minor frown lines 6 months after treatment. Between 3% and 5% of patients in clinical studies had no or minor frown lines 9 months after treatment. In other safety studies, between 5% and 17% of patients still had noticeable improvement 9 months later.

Q: Will I need the same number of units as my current frown line treatment?

A: In short, no, and here’s why. Units are like fingerprints—they are a proprietary measurement of a treatment’s unique potency. Because of the differences in how treatments are formulated and tested, you cannot compare or convert Units between them, just like you cannot compare 2 fingerprints. A clearer way to understand dosing is to look at how many nanograms of active ingredient (botulinum toxin type A) a product has. Double the Units does not mean double the dose DAXXIFY™ Approved frown line dose: 40 Units Amount of active ingredient: 0.18 nanograms BOTOX® Cosmetic Approved frown line dose: 20 Units Amount of active ingredient: 0.18 nanograms DYSPORT® Approved frown line dose: 50 Units Amount of active ingredient: 0.27 nanograms As you can see, despite the number of Units, DAXXIFY™ isn’t 2x the dose of BOTOX® Cosmetic, nor is Dysport® 2.5x the dose of BOTOX® Cosmetic. Talk to your provider about DAXXIFY™ and your aesthetic goals.

Q: Do long-lasting results mean Potentially long-lasting side effects?

A: No, not necessarily. The most common side effects observed in clinical trials occurred within one to two weeks after injection and lasted only a short while. This is consistent with other frown line treatments. DAXXIFY™ is well-studied, with no serious treatment-related side effects seen in large-scale clinical trials.

Q: How often will I need to get DAXXIFY™ and when will I See results?

A: If you’re like most people, you probably get a frown line treatment around twice a year. But here’s the thing: conventional treatments only last 3–4 months. That means you may spend the next 2-3 months of the year with those frown lines staring back at you between treatments. That’s up to 4-6 months of total wear off time per year! • DAXXIFY™ is different. With those same 2 treatment visits, you can keep your frown lines smoother for a full year!§ • §At least 50% of patients in clinical studies had no or minor frown lines 6 months after treatment. • You may see results with DAXXIFY™ as early as the next day after treatment, and typically within two days.

Q: Is DAXXIFY™ well studied?

A: DAXXIFY™ was studied in the largest-ever clinical study conducted for a frown line treatment and included more than 2,400 people across different ages and skin types. • There were no serious treatment-related side effects in clinical trials for DAXXIFY™. • The active ingredient in DAXXIFY™ is botulinum toxin type A, an ingredient that has been used in frown line treatments for more than 20 years. 96% of people treated with DAXXIFY™ were satisfied with their results† • †96% of patients reported they were satisfied on a 7-point scale when evaluated at 4 weeks in clinical studies.

Q: Is DAXXIFY™ safe?

A: DAXXIFY™ was studied in the largest-ever clinical study for a frown line treatment and included more than 2,800 people across different ages and skin types. Here are some things you should know about DAXXIFY™: • There were no serious treatment-related side effects • The active ingredient in DAXXIFY™ is botulinum toxin type A, an ingredient that has been used in frown line treatments for more than 20 years • 96% of people treated with DAXXIFY™ were satisfied with their results‡ • ‡96% of patients reported they were satisfied on a 7-point scale when evaluated at 4 weeks in clinical studies. • The safety and efficacy of DAXXIFY™ is well established, with more than 20 years of research. In fact, DAXXIFY™ has been studied in the largest ever phase 3 clinical trial program conducted for a frown line treatment and included more than 2,400 people across different ages and with different skin types. There were no notable differences in how DAXXIFY™ performed in clinical trial patients with varying skin types.

Q: How should I prepare for my DAXXIFY™ treatment?

A: Ask your aesthetic provider for pre-treatment instructions prior to your DAXXIFY™ appointment. A list of common avoidances before treatment include, but are not limited to: Retin-A Blood thinners Muscle relaxants Fish or oils rich in omega 3 Allergy medication Topical steroids Sleep medications and supplements Aspirin St. John’s Wort Supplements containing Vitamin E Ibuprofen

Q: Why are peptides important?

A: All frown line treatments require a special ingredient to stabilize botulinum toxin A, the protein responsible for helping smooth moderate to severe frown lines. For instance, BOTOX® Cosmetic uses human serum albumin (HSA), a blood product, as its stabilizer. Dysport®, another frown line treatment, uses HSA as a stabilizer and cow’s milk protein as a protectant. DAXXIFY™ is unique because it is the only formulation that uses a novel peptide as a stabilizer and does not contain human or animal byproducts.

Frequently Asked Questions

Q: What is DAXXIFY™ and how is it different?

A: DAXXIFY™ is FDA-approved to help smooth moderate to severe lines between the brows. It is the only long-lasting frown line treatment powered by a peptide with results that last on average 6 months and up to 9 months for some. Produced by Revance Therapeutics, Daxxify is a revolutionary new product.

Q: How is DAXXIFY™ different from Other frown line treatments?

A: DAXXIFY™ is the only long-lasting frown line treatment powered by a peptide. Results last on average 6 months and up to 9 months for some. † • All frown line treatments require a special ingredient to stabilize botulinum toxin A, the protein responsible for helping smooth moderate to severe frown lines. For instance, BOTOX® Cosmetic uses human serum albumin (HSA), a blood product, as its stabilizer. Dysport®, another frown line treatment, uses HSA as a stabilizer and cow’s milk protein as a protectant. • DAXXIFY™ is unique because it is the only formulation that uses a novel peptide as a stabilizer and does not contain human or animal byproducts. • †At least 50% of patients in clinical studies had no or minor frown lines 6 months after treatment. Between 3% and 5% of patients in clinical studies had no or minor frown lines 9 months after treatment. In other safety studies, between 5% and 17% of patients still had noticeable improvement 9 months later.

Q: Will I need the same number of units as my current frown line treatment?

A: In short, no, and here’s why. Units are like fingerprints—they are a proprietary measurement of a treatment’s unique potency. Because of the differences in how treatments are formulated and tested, you cannot compare or convert Units between them, just like you cannot compare 2 fingerprints. A clearer way to understand dosing is to look at how many nanograms of active ingredient (botulinum toxin type A) a product has. Double the Units does not mean double the dose DAXXIFY™ Approved frown line dose: 40 Units Amount of active ingredient: 0.18 nanograms BOTOX® Cosmetic Approved frown line dose: 20 Units Amount of active ingredient: 0.18 nanograms DYSPORT® Approved frown line dose: 50 Units Amount of active ingredient: 0.27 nanograms As you can see, despite the number of Units, DAXXIFY™ isn’t 2x the dose of BOTOX® Cosmetic, nor is Dysport® 2.5x the dose of BOTOX® Cosmetic. Talk to your provider about DAXXIFY™ and your aesthetic goals.

Q: Is DAXXIFY™ safe?

A: DAXXIFY™ was studied in the largest-ever clinical study for a frown line treatment and included more than 2,800 people across different ages and skin types. Here are some things you should know about DAXXIFY™: • There were no serious treatment-related side effects • The active ingredient in DAXXIFY™ is botulinum toxin type A, an ingredient that has been used in frown line treatments for more than 20 years • 96% of people treated with DAXXIFY™ were satisfied with their results‡ • ‡96% of patients reported they were satisfied on a 7-point scale when evaluated at 4 weeks in clinical studies. • The safety and efficacy of DAXXIFY™ is well established, with more than 20 years of research. In fact, DAXXIFY™ has been studied in the largest ever phase 3 clinical trial program conducted for a frown line treatment and included more than 2,400 people across different ages and with different skin types. There were no notable differences in how DAXXIFY™ performed in clinical trial patients with varying skin types.

Q: Do long-lasting results mean Potentially long-lasting side effects?

A: No, not necessarily. The most common side effects observed in clinical trials occurred within one to two weeks after injection and lasted only a short while. This is consistent with other frown line treatments. DAXXIFY™ is well-studied, with no serious treatment-related side effects seen in large-scale clinical trials.

Q: How should I prepare for my DAXXIFY™ treatment?

A: Ask your aesthetic provider for pre-treatment instructions prior to your DAXXIFY™ appointment. A list of common avoidances before treatment include, but are not limited to: Retin-A Blood thinners Muscle relaxants Fish or oils rich in omega 3 Allergy medication Topical steroids Sleep medications and supplements Aspirin St. John’s Wort Supplements containing Vitamin E Ibuprofen

Q: How often will I need to get DAXXIFY™ and when will I See results?

A: If you’re like most people, you probably get a frown line treatment around twice a year. But here’s the thing: conventional treatments only last 3–4 months. That means you may spend the next 2-3 months of the year with those frown lines staring back at you between treatments. That’s up to 4-6 months of total wear off time per year! • DAXXIFY™ is different. With those same 2 treatment visits, you can keep your frown lines smoother for a full year!§ • §At least 50% of patients in clinical studies had no or minor frown lines 6 months after treatment. • You may see results with DAXXIFY™ as early as the next day after treatment, and typically within two days.

Q: Why are peptides important?

A: All frown line treatments require a special ingredient to stabilize botulinum toxin A, the protein responsible for helping smooth moderate to severe frown lines. For instance, BOTOX® Cosmetic uses human serum albumin (HSA), a blood product, as its stabilizer. Dysport®, another frown line treatment, uses HSA as a stabilizer and cow’s milk protein as a protectant. DAXXIFY™ is unique because it is the only formulation that uses a novel peptide as a stabilizer and does not contain human or animal byproducts.

Q: Is DAXXIFY™ well studied?

A: DAXXIFY™ was studied in the largest-ever clinical study conducted for a frown line treatment and included more than 2,400 people across different ages and skin types. • There were no serious treatment-related side effects in clinical trials for DAXXIFY™. • The active ingredient in DAXXIFY™ is botulinum toxin type A, an ingredient that has been used in frown line treatments for more than 20 years. 96% of people treated with DAXXIFY™ were satisfied with their results† • †96% of patients reported they were satisfied on a 7-point scale when evaluated at 4 weeks in clinical studies.

Before/After Library

DAXXIFY™, Frown Line Treatment

*At least 50% of patients in clinical studies had no or minor frown lines 6 months after treatment. Between 3% and 5% of patients in clinical studies had no or minor frown lines 9 months after treatment. In other safety studies, between 5% and 17% of patients still had noticeable improvement 9 months later.

Learn More: Safety Information

IMPORTANT SAFETY INFORMATION for DAXXIFY™ (daxibotulinumtoxinA-Ianm) injection:

  • • DAXXIFY™ may cause serious side effects that can be life threatening. Get medical help right away if you have any of these problems any time (hours to weeks) after injection of DAXXIFY™:
  • • Problems swallowing, speaking, or breathing due to weakening of associated muscles can be severe and result in loss of life. You are at the highest risk if these problems are pre-existing before injection. Swallowing problems may last for several months.
  • • Spread of toxin effects. The effect of botulinum toxin may affect areas away from the injection site and cause serious symptoms that include loss of strength and all-over muscle weakness, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, and trouble swallowing.
  • • Do not receive DAXXIFY™ if you are allergic to any of the ingredients in DAXXIFY™ (see Medication Guide for ingredients); had an allergic reaction to any other botulinum toxin product such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA (BOTOX®/BOTOX® Cosmetic), abobotulinumtoxinA (DYSPORT®), incobotulinumtoxinA (XEOMIN®) or prabotulinumtoxinA-xvfs (JEUVEAU®); or have a skin infection at the planned injection site.
  • • DAXXIFY™ dosing units are not the same as, or comparable to, any other botulinum toxin product.
  • • Tell your healthcare provider about all your medical conditions, including any side effects from botulinum toxin products, including dry eye; breathing, swallowing, bleeding, or heart problems; plans to have surgery; weakness of forehead muscles; drooping eyelids; have had surgery on your face; are pregnant or breastfeeding or plan to become pregnant or breastfeed.
  • • Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
  • • Using DAXXIFY™ with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your healthcare provider that you have received DAXXIFY™ in the past.
  • • Especially tell your healthcare provider if you have received any other botulinum toxin product in the last 4 months or any in the past, and exactly which product you received (such as BOTOX®, BOTOX® Cosmetic, MYOBLOC®, DYSPORT®, XEOMIN®, or JEUVEAU®). DAXXIFY™ may cause serious side effects, including allergic reactions (such as itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint), heart problems (such as irregular heartbeat and heart attack), and eye problems (including dry eye, reduced blinking, and corneal problems). Tell your healthcare provider or get medical help right away if you experience a serious side effect. No serious adverse events of distant spread of toxin effect associated with dermatologic use of DAXXIFY™ have been reported in clinical studies at the dose of 40 Units for glabellar lines. The most common side effects of DAXXIFY™ include headache, eyelid drooping, and loss of ability to move the muscles in your face.
  • • These are not all the possible side effects of DAXXIFY™. For more information, see the full Prescribing Information including Boxed Warning, and refer to the Medication Guide or talk with your doctor. To report side effects associated with DAXXIFY™, please call 1-877-373-8669. You may also report side effects to the FDA at 1-800-FDA-1088 or visit www.fda.gov/medwatch.

    APPROVED USE
    DAXXIFY™ is a prescription medicine that is injected into muscles and used in adults to temporarily improve the look of moderate to severe frown lines between the eyebrows. DAXI-001723

Find DAXXIFY™ In:

Hunt Valley, Knoxville, West Knoxville, & Sevierville • Coming soon to Virginia Beach!

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